Description
Botulax 300 is the highest-dose format available in the Botulax range, produced by Hugel Pharma in South Korea. Each vial contains 300 units of purified Clostridium botulinum toxin type A (CBFC26 strain), combined with stabilizers such as human serum albumin and sodium chloride to ensure purity, safety, and long-term stability. This large-dose vial is ideal for professional clinics performing multiple treatments per session or addressing large therapeutic areas.
Mechanism of Action
Like other Botulax formulations, Botulax 300 works by inhibiting acetylcholine release at the neuromuscular junction. This prevents targeted muscle contraction, resulting in smoother skin, reduced expression lines, and relief from muscular conditions. The effects typically last 4–6 months, with patients noticing visible results within 2–3 days of injection.
Key Benefits & Uses
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Aesthetic Applications: Smooths deep forehead wrinkles, glabellar frown lines, crow’s feet, chin dimpling, and horizontal neck bands
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Facial Contouring: Jawline slimming, brow lift, and lip shape correction
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Therapeutic Benefits: Treatment of bruxism, blepharospasm, cervical dystonia, muscle stiffness, and hyperhidrosis (excessive sweating)
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Clinic Efficiency: With 300 units per vial, practitioners can perform multiple procedures with one reconstitution, making it cost-effective and time-saving
Storage & Handling Instructions
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Supplied as a lyophilized sterile white powder in a sealed vial
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Must be stored refrigerated at 2–8 °C; avoid freezing or sunlight exposure
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Shelf life: Up to 36 months unopened, if properly stored
Reconstitution & Usage Guidelines
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Requires sterile 0.9% saline for dilution (not included, must be sourced separately)
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Standard dilution: 7.5 mL saline per 300 U vial, giving approx. 4 units per 0.1 mL
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Use within 24 hours of reconstitution; refrigerated solution may retain potency for up to 72 hours
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Administer with fine-gauge needles (24–30 G) by qualified professionals under aseptic technique
Safety Profile
When injected correctly, Botulax 300 is safe and effective. Most side effects are mild and temporary, such as swelling, redness, or bruising at the injection site. Rare effects like drooping of the eyelid or brow are self-limiting and typically resolve naturally. Its performance and safety are considered comparable to Botox, making it a trusted, cost-effective alternative.
Why Choose Botulax 300?
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Largest-dose format in the Botulax range, designed for clinics with higher patient turnover
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Cost-effective option per unit, allowing multiple procedures from one vial
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Authentic Korean version produced under strict GMP standards
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Reliable potency control ensures consistent and predictable outcomes
Botulax 300 FAQ Quick Reference
Question | Answer |
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What is Botulax 300? | A high-dose (300 units) Korean botulinum toxin type A for cosmetic and therapeutic treatments. |
How should it be stored? | Refrigerated at 2–8 °C, never frozen. Shelf life up to 36 months unopened. |
Does it come with saline? | No. Sterile 0.9% saline must be sourced separately for reconstitution. |
How do I reconstitute Botulax 300? | Standard dilution: 7.5 mL saline per vial (approx. 4 U per 0.1 mL). |
How long does it last once mixed? | Best used within 24 hours; up to 72 hours if refrigerated. |
How soon are results visible? | Typically within 2–3 days. |
How long do results last? | Around 4–6 months, depending on the treatment and patient response. |

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